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ARFGEF2

ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)

Synonyms:
BIG2, PVNH2, dJ1164I10.1
Species:
UniProtKB ID:
Gene ID:
  • Human(10564) Summary: ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
  • Mouse(99371) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
  • Rat(296380) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
  • naked mole-rat(101706311) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
  • dog(477256) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
  • domestic cat(101082556) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
  • domestic guinea pig(100724838) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
  • sheep(101116164) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
  • Horse(100071351) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
  • cow(539295) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
  • chicken(419211) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
  • Zebrafish(100334572) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ARFGEF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ARFGEF2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-BIG2 Antibody, clone 56, clone 56, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Arfgef2,
Species
mouse
MISSION® esiRNA, targeting human ARFGEF2,
Species
human