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ARFGAP3

ADP-ribosylation factor GTPase activating protein 3

Synonyms:
ARFGAP1
Species:
UniProtKB ID:
Gene ID:
  • Human(26286) Summary: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]
  • Mouse(66251) ADP-ribosylation factor GTPase activating protein 3
  • Rat(503165) ADP-ribosylation factor GTPase activating protein 3
  • sheep(101115447) ADP-ribosylation factor GTPase activating protein 3
  • cow(532778) ADP-ribosylation factor GTPase activating protein 3
  • naked mole-rat(101717408) ADP-ribosylation factor GTPase activating protein 3
  • Zebrafish(402889) ADP-ribosylation factor GTPase activating protein 3
  • fruit fly(40487) ADP-ribosylation factor GTPase activating protein 3
  • domestic cat(101091637) ADP-ribosylation factor GTPase activating protein 3
  • dog(474477) ADP-ribosylation factor GTPase activating protein 3
  • chicken(418224) ADP-ribosylation factor GTPase activating protein 3
  • domestic guinea pig(100725575) ADP-ribosylation factor GTPase activating protein 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ARFGAP3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
Anti-ARFGAP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ARFGAP3,
Species
human
MISSION® esiRNA, targeting mouse Arfgap3,
Species
mouse