Skip to Content
Merck
All Photos(2)

Documents

MAK109

Sigma-Aldrich

LPL Activity Assay Kit

Supplied by Roar Biomedical, Inc.

Synonym(s):

Lipoprotein lipase activity assay kit

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12161503
NACRES:
NA.84

usage

sufficient for 100 fluorometric tests

application(s)

pharmaceutical

detection method

fluorometric

relevant disease(s)

gastrointestinal diseases; cardiovascular diseases

storage temp.

2-8°C

Gene Information

human ... LPL(4023)

General description

Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.

Application

LPL Activity Assay Kit may be used for detection of LPL activity in plasma samples of patients with hypertriglyceridemia.

Suitability

Suitable for the measurement of lipoprotein lipase activity in a variety of tissue samples

Principle

The LPL Activity Assay Kit includes a non-fluorescent substrate emulsion that becomes intensely fluorescent upon interaction with LPL and pre-hydrolyzed substrate for use as a standard to convert the fluorescence intensity reading to moles of reactant formed (λEx=370 nm/λEm=450 nm). The assay is not specific for LPL and will also detect hepatic lipase activity.

related product

Storage Class Code

10 - Combustible liquids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Prabodh Sadana et al.
International journal of molecular sciences, 21(20) (2020-10-15)
Mice fed a high-fat diet for 12 weeks or longer develop hyperglycemia, insulin resistance, dyslipidemia, and fatty liver. Additionally, a high-fat diet induces inflammation that remodels and affects the anti-inflammatory and antiatherogenic property of the high-density lipoprotein (HDL). However, the
Maria Notarnicola et al.
Lipids in health and disease, 11, 145-145 (2012-11-01)
Lipid metabolism is altered in subjects with liver steatosis. FAS is a key enzyme in de novo lipogenesis and both FAS gene expression and enzymatic activity are primarily regulated by metabolic signals in the liver. Lipoprotein lipase (LPL), the rate-limiting
Hung-Yu Sun et al.
Gut, 62(8), 1193-1203 (2012-06-13)
Circulating hepatitis C virus (HCV) virions are associated with triglyceride-rich lipoproteins, including very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), designated as lipo-viro-particles (LVPs). Previous studies showed that lipoprotein lipase (LPL), a key enzyme for hydrolysing the triglyceride in VLDL
Chaofeng Yang et al.
Nutrition & metabolism, 9(1), 94-94 (2012-10-31)
Endocrine FGF19 and FGF21 exert their effects on metabolic homeostasis through fibroblast growth factor receptor (FGFR) and co-factor betaKlotho (KLB). Ileal FGF19 regulates bile acid metabolism through specifically FGFR4-KLB in hepatocytes where FGFR1 is not significant. Both FGF19 and FGF21
Tomomi Yamazaki et al.
Journal of lipid research, 53(10), 2024-2037 (2012-06-28)
Postprandial hyperlipidemia (lipemia) is a risk factor for atherosclerosis. However, mouse models of postprandial hyperlipidemia have not been reported. Here, we report that ddY mice display marked postprandial hypertriglyceridemia in response to dietary fat. In ddY mice, the fasting serum

Protocols

Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service