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Supelco

Febantel

VETRANAL®, analytical standard

Synonym(s):

N-{2-[2,3-Bis-(methoxycarbonyl)-guanido]-5-(phenylthio)-phenyl}-2-methoxyacetamide

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About This Item

Empirical Formula (Hill Notation):
C20H22N4O6S
CAS Number:
Molecular Weight:
446.48
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

COCC(=O)Nc1cc(Sc2ccccc2)ccc1\N=C(\NC(=O)OC)NC(=O)OC

InChI

1S/C20H22N4O6S/c1-28-12-17(25)21-16-11-14(31-13-7-5-4-6-8-13)9-10-15(16)22-18(23-19(26)29-2)24-20(27)30-3/h4-11H,12H2,1-3H3,(H,21,25)(H2,22,23,24,26,27)

InChI key

HMCCXLBXIJMERM-UHFFFAOYSA-N

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Application

Febantel may be used as a reference standard in the determination of febantel in samples of animal feed and pharmaceutical formulations, using high performance liquid chromatography (HPLC) and high performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS-MS), respectively.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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H Mehlhorn et al.
Parasitology research, 83(5), 419-434 (1997-01-01)
The present study proved that combined administration of pyrantel and febantel to Heterakis spumosa-infected mice yielded clear synergistic effects (seen in a quicker expulsion of the worms and a significant higher degree of worm degeneration), whereas the different doses of
P N Prelezov et al.
DTW. Deutsche tierarztliche Wochenschrift, 110(10), 419-421 (2003-12-04)
Fourteen of 23 dogs developing patent Trichuris vulpis infections by 120 days p.i. with 5000 embryonated eggs were allocated into three groups. One group was treated with flubendazole 220 mg chewable tablets (Flubenol) at the recommended dose regimen once daily
Guadalupe Miró et al.
Parasitology research, 100(2), 317-320 (2006-08-18)
Using routine coprological methods, 1161 faecal samples from animal shelters located in Madrid (Spain) were analysed, showing a 28% prevalence for different intestinal parasites: Giardia duodenalis (7%), Cystoisopora spp. (3.8%), Toxocara canis (7.8%), Toxascaris leonina (6.3%), Ancylostomidae (4%), Trichuris vulpis
Residues of some veterinary drugs in animals and foods. Joint FAO/WHO Expert Committee on Food Additives.
FAO food and nutrition paper, 41(8), 1-166 (1996-01-01)
Efficacy of pyrantel embonate, febantel and praziquantel against Giardia species in naturally infected adult dogs.
A Giangaspero et al.
The Veterinary record, 150(6), 184-186 (2002-03-13)

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