00200595

Quercetin dihydrate

primary reference standard

• Synonym(s): 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3′,4′,5,7-Pentahydroxyflavone dihydrate
• Empirical Formula (Hill Notation): C₁₅H₁₀O₇ · 2H₂O
• CAS Number: 6151-25-3
• Molecular Weight: 338.27
• Colour Index Number: 75670
• Beilstein: 317313
• EC Number: 204-187-1
• UNSPSC Code: 85151701
• NACRES: NA.24

Properties

• grade: primary reference standard
• form: powder
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: HWI
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: >300 °C (lit.)
• SMILES string: OC(C(O)=C1)=CC=C1C2=C(O)C(C3=C(O)C=C(O)C=C3O2)=O
• InChI: 1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2
• InChI key: GMGIWEZSKCNYSW-UHFFFAOYSA-N

Description

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference standard in the analysis of herbal medicinal products.

Biochem/physiol Actions

Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

Other Notes

This compound is commonly found in plants of the genus: allium angelica arnica carum echinacea eucalyptus ginkgo glycyrrhiza lycium pimpinella primula sambucus silybum

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301
• Precautionary Statements: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1