- Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA.
Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA.
Journal of inorganic biochemistry (2012-07-24)
A G Quiroga
PMID22819649
ABSTRACT
This focused review is devoted to our advances in developing trans platinum complexes as antitumoral complexes, in particular those bearing aliphatic amines. It includes some fundamental aspects of the understanding of non conventional metallodrug mechanism. The perspective is arranged by those fundamental aspects and within each section only the most successful examples have been included and also those in which clearly SAR's (structure activity relationships) have been observed.
MATERIALS
Product Number
Brand
Product Description
Platinum, foil, not light tested, 50x50mm, thickness 0.005mm, as rolled, 99.95%
Platinum, foil, not light tested, 50x50mm, thickness 0.004mm, as rolled, 99.95%
Platinum, tube, 100mm, outside diameter 3.0mm, inside diameter 2.8mm, wall thickness 0.1mm, as drawn, 99.95%
Platinum, microfoil, disks, 25mm, thinness 0.1μm, specific density 120μg/cm2, permanent mylar 3.5μm support, 99.99%
Platinum, foil, 25x25mm, thickness 0.25mm, as rolled, 99.99+%
Platinum, rod, 25mm, diameter 1.0mm, 99.95%
Platinum, foil, 30x30mm, thickness 0.2mm, as rolled, 99.95%
Platinum, wire reel, 0.05m, diameter 0.8mm, annealed, may be used as one component of a thermocouple, 99.99%
Platinum, rod, 10mm, diameter 4.0mm, 99.95%
Platinum, foil, 10mm disks, thickness 0.125mm, as rolled, 99.95%
Platinum, insulated wire, 5m, conductor diameter 0.05mm, insulation thickness 0.009mm, PTFE (polytetrafluoroethylene) insulation, 99.99%
Platinum, tube, 200mm, outside diameter 0.95mm, inside diameter 0.60mm, wall thickness 0.175mm, as drawn, 99.95%
Platinum, wire reel, 0.05m, diameter 1.0mm, annealed, may be used as one component of a thermocouple, 99.99%
Platinum, foil, 15x15mm, thickness 0.2mm, as rolled, 99.95%
Platinum, wire reel, 0.05m, diameter 1.0mm, as drawn, 99.99+%
Platinum, foil, 8mm disks, thickness 0.004mm, as rolled, 99.95%
Platinum, foil, 10mm disks, thickness 0.125mm, as rolled, 99.99+%
Platinum, wire reel, 0.1m, diameter 0.15mm, annealed, may be used as one component of a thermocouple, 99.99%