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  • T cell non-Hodgkin's lymphoma with colesional mucormycosis presenting as palatal perforation: a case report.

T cell non-Hodgkin's lymphoma with colesional mucormycosis presenting as palatal perforation: a case report.

Journal of the Indian Medical Association (2013-03-26)
Afaq Ahmad Khan, Ambuj Garg, Shashi Dhawan, Pankaj Kumar Agarwal, Fouzia Siraj, Shyam Aggarwal
ABSTRACT

Non-Hodgkin's lymphoma (NHL) is predominantly a disease of lymph nodes, but extranodal involvement is not very uncommon. Palatal involvement by NHL is rare. Mucormycosis is a devastating fungal infection commonly seen in immunocompromised individuals, including those with NHL, but it is affecting the same region has been reported very rarely. Simultaneous infiltration of hard palate by NHL and mucormycosis is extremely unusual. Herein we describe a patient who presented with palatal hole with histopathological examination revealing presence of lymphoma with colesional mucormycosis. The identification of mucor was vital because chemotherapy alone in the absence of antifungals would have had devastating consequences as the mortality of untreated mucormycosis is high.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Amphotericin B solubilized, powder, γ-irradiated, BioXtra, suitable for cell culture
Sigma-Aldrich
Amphotericin B solution, 250 μg/mL in deionized water, 0.1 μm filtered, BioReagent, suitable for cell culture
Sigma-Aldrich
Amphotericin B from Streptomyces sp., ~80% (HPLC), powder
Sigma-Aldrich
Amphotericin B from Streptomyces sp., BioReagent, suitable for cell culture, ~80% (HPLC)
Amphotericin B for peak identification, European Pharmacopoeia (EP) Reference Standard