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P8043

Sigma-Aldrich

D-Psicose

≥95% (HPLC)

Synonym(s):

(3R,4R,5R)-1,3,4,5,6-pentahydroxyhexan-2-one, D-ribo-2-Hexulose

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
551-68-8
Molecular Weight:
180.16
EC Number:
208-999-7
MDL number:
MFCD00083478
UNSPSC Code:
12352201
PubChem Substance ID:
24898906
NACRES:
NA.25

biological source

synthetic (organic)

Assay

≥95% (HPLC)

form

solid

impurities

≤25% water (Karl Fischer)

solubility

water: 100 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

OC[C@H](O)[C@@H](O)[C@@H](O)C(=O)CO

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5+,6-/m0/s1

InChI key

BJHIKXHVCXFQLS-LFRDXLMFSA-N

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General description

D-Psicose protects and preserves pancreatic β-islets through the maintenance of hyperglycemia and by the prevention of fat accumulation in Otsuka Long-Evans Tokushima Fatty rats.

Application

D-Psicose has been used in a study to assess the bioconversion of D-fructose to D-allose. It has also been used in a study that investigated the characteristics and antioxidant activity of maillard reaction products.

Other Notes

Mixed anomers
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bioconversion of D-fructose to D-allose by novel isomerases
Bai, W., et al.
Sheng Wu Gong Cheng Xue Bao (Chinese journal of biotechnology), 28, 28-28 (2012)
Wanmeng Mu et al.
Applied microbiology and biotechnology, 94(6), 1461-1467 (2012-05-10)
D-Psicose is a hexoketose monosaccharide sweetener, which is a C-3 epimer of D-fructose and is rarely found in nature. It has 70 % relative sweetness but 0.3 % energy of sucrose, and is suggested as an ideal sucrose substitute for
Jingxuan Zhu et al.
Frontiers in chemistry, 6, 437-437 (2018-10-16)
The scarcity, richness, and other important physiological functions of D-psicose make it crucial to increase the yield of D-psicose. The production of D-psicose can be accomplished by D-psicose 3-epimerase (DPEase) from Clostridium bolteae (CbDPEase) catalyzing the substrate D-fructose. Although the
Noriko Hayashi et al.
Bioscience, biotechnology, and biochemistry, 74(3), 510-519 (2010-03-09)
This clinical study was conducted to investigate the safety and effect of D-psicose on postprandial blood glucose levels in adult men and women, including borderline diabetes patients. A randomized double-blind placebo-controlled crossover experiment of single ingestion was conducted on 26
Young-Mee Chung et al.
Journal of food science, 77(2), H53-H58 (2012-02-22)
D-Psicose, a C-3 epimer of D-fructose, has shown promise in reducing body fat accumulation in normal rats and plasma glucose level in genetic diabetic mice. Effects of D-psicose on diet-induced obesity are not clearly elucidated, and we investigated food intake
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