Activation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats.

Activation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats.

Frontiers in pharmacology (2017-05-26)

Jing Yang, Lixin Sun, Lu Wang, Hozeifa M Hassan, Xuan Wang, Phillip B Hylemon, Tao Wang, Huiping Zhou, Luyong Zhang, Zhenzhou Jiang

ABSTRACT

Triptolide (TP), a diterpenoid isolated from

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

GW4064, ≥97% (HPLC)