- A concise asymmetric synthesis of torcetrapib.
A concise asymmetric synthesis of torcetrapib.
The Journal of organic chemistry (2007-07-13)
Meritxell Guinó, Pim Huat Phua, Jean-Claude Caille, King Kuok Mimi Hii
PMID17625891
ABSTRACT
Optically active torcetrapib was synthesized in seven steps from achiral precursors without the need for protecting groups, utilizing an enantioselective aza-Michael reaction to achieve asymmetry.
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