- [The synthesis and anti-inflammatory properties of 7-theophyllineacetic acid derivatives].
[The synthesis and anti-inflammatory properties of 7-theophyllineacetic acid derivatives].
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi (1990-10-01)
G Dănilă, M Ungureanu, M Pavelescu, G Rusu, I Sandu
PMID2131555
ABSTRACT
Some esters of 7-theophyllinylacetic acid were synthetized, characterized physicochemically and tested for their anti-inflammatory properties. As compared to indomethacin, reference anti-inflammatory drug, all synthetized compounds were less toxic. The anti-inflammatory properties are influenced by the nature of the ester group radicals, the more active having ramified alchils.