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  • Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA.

Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA.

Chemical communications (Cambridge, England) (2005-02-23)
Anca Dragulescu-Andrasi, Peng Zhou, Gaofei He, Danith H Ly
ABSTRACT

Guanidine-based peptide nucleic acid (GPNA) with a d-backbone configuration and alternate spacing binds sequence-specifically to RNA and is readily taken up by both human somatic and embryonic stem (ES) cells.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
N-Glutaryl-L-phenylalanine p-nitroanilide, protease substrate