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Merck

CRISPR/Cas9 Products

Design and order CRISPR gRNA, Cas9, screening libraries, controls and companion products. Formats include plant, lentivirus, IVT-RNA, plasmid, synthetic, and protein. 

Product Product Description 
Pre-designed CRISPR gRNAs- Synthetic SygRNA® gRNAs available in two-part (crRNA:tracrRNA) or one-part sgRNA formats.
- Perfect for animal model generation and cell model engineering.
- Recommended to complex with Cas9 protein.
- Lentivirus gRNAs are available as ready-to-use lentivirus transduction particles.
- Perfect for difficult-to-transfect or primary cells.
- Plasmid DNA transfection-grade plasmid gRNAs available in a variety of vectors.
- Perfect for transfection, nucleofection, and lentiviral packaging (Note: lentiviral packaging can only be achieved by selecting a lentiviral vector).
- In Vitro Transcribed RNA  is provided in DNase-, RNase-, and protease-free molecular-grade water.
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Design CRISPR- Click on the CRISPR Design Tool to get started.
- Select your desired genome, choose your gene of interest, and set parameters for the designs.
- View and export a list of ranked gRNAs.
Design CRISPR
CRISPR  gRNAs- Click on the Order gRNAs button and upload your gRNA sequences.
- Choose the format: Synthetic gRNA, Transfection-grade plasmid DNA, Lentiviral transduction particles, or IVT gRNA.
- Customize the vector and configuration.
- Visit the CRISPR Essentials page to compare options.
- Purchase clone quantities to receive additional discounts.
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Sanger Whole Genome Knockout (KO) Arrayed CRISPR Libraries- Over 74,000 individual off-the-shelf CRISPR gRNAs designed to maximize KO of every protein-coding gene in human and mouse genomes.
- Available as individual clones, gene panels, and whole genome libraries.
 
Sanger QuickPick™ KO gRNAs- A fast, cost-efficient way to quickly knock out your gene of interest.
- Available formats: Bacteria Glycerol Stocks, Plasmid DNA, Lentiviral transduction particles
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Whole Genome KO Pooled Libraries- GeCKO v2 CRISPR Knockout Pooled Libraries
- Available for human and mouse genomes
- Vector options: lentiCRISPRv2 (Cas9+gRNA on same vector); lentiGuide-Puro (gRNA-only vector)
 
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