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SML3821

Sigma-Aldrich

CAS-12290-201

≥98% (HPLC)

Synonym(s):

3-((1-(2-chloroacetyl)azetidin-3-yl)methyl)-7-fluoroquinazolin-4(3H)-one

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About This Item

Empirical Formula (Hill Notation):
C14H13ClFN3O2
Molecular Weight:
309.72
UNSPSC Code:
12352200
NACRES:
NA.21

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

2-8°C

Biochem/physiol Actions

CAS-12290-201, a fluoroquinazolinone compound, is cell penetrant, selective and potent chemical probe for deubiquitinating enzymes (DUB) VCPIP1. CAS-12290-201 covalently labels the catalytic cysteine of VCPIP1.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Accelerating inhibitor discovery for deubiquitinating enzymes
Nature Communications, 14(1), 686-686 (2023)

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