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Key Documents

SAB5702830

Sigma-Aldrich

Anti-IRF6 Antibody, clone 5D1Z4, Rabbit Monoclonal

Synonym(s):

LPS, OFC6, PIT, PPS, PPS1, VWS, VWS1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

material

colorless

clone

5D1Z4, monoclonal

form

liquid

mol wt

68 kDa

species reactivity

rat, rat, human

concentration

1.00 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200
immunoprecipitation (IP): 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

PFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPTPSMQLPPALPPQ

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IRF6(3664)

General description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 368-467 of human IRF6 (O14896).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC, IP

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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