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Sigma-Aldrich

Poly(D,L-lactide-co-glycolide)

average Mw 5,000-15,000, lactide:glycolide (50:50)

Synonym(s):

PLGA

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About This Item

Linear Formula:
[C3H4O2]x[C2H2O2]y
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:

feed ratio

lactide:glycolide (50:50)

mol wt

average Mw 5,000-15,000

inherent viscosity

0.15-0.25 dL/g(lit.)

transition temp

Tg (DSC) 24 °C (onset)

SMILES string

OCC(O)=O.CC(O)C(O)=O

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Features and Benefits

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

Physical form

Biocompatible, biodegradable polymer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Claus G Madsen et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 92, 1-7 (2015-02-11)
This study describes how protein release from polymer matrices correlate with simple measurements on the intrinsic viscosity of the polymer solutions used for casting the matrices and calculations of the solubility parameters of polymers and solvents used. Matrices of poly(dl-lactide-co-glycolide)

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