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U2AF2

U2 small nuclear RNA auxiliary factor 2

Synonyms:
U2AF65
Species:
UniProtKB ID:
Gene ID:
  • Human(11338) Summary: U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]
  • Mouse(22185) U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
  • Rat(308335) U2 small nuclear RNA auxiliary factor 2
  • dog(100687048) U2 small nuclear RNA auxiliary factor 2
  • Horse(100050729) U2 small nuclear RNA auxiliary factor 2
  • cow(507895) U2 small nuclear RNA auxiliary factor 2
  • sheep(101117445) U2 small nuclear RNA auxiliary factor 2
  • domestic guinea pig(100733836) U2 small nuclear RNA auxiliary factor 2
  • naked mole-rat(101725252) U2 small nuclear RNA auxiliary factor 2
  • domestic cat(101082705) U2 small nuclear RNA auxiliary factor 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-U2AF2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rat
Application
western blot
Anti-U2AF2/U2AF65 Antibody, clone 8E8R9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-U2AF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-U2AF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-U2AF65 antibody, Mouse monoclonal, clone MC3, purified from hybridoma cell culture,
Species Reactivity
xenopus, human, mouse, rat
Application
ELISA
electron microscopy

immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

microarray

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse U2af2,
Species
mouse
MISSION® esiRNA, targeting human U2AF2,
Species
human