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Merck

SUN2

Sad1 and UNC84 domain containing 2

Synonyms:
UNC84B
Species:
UniProtKB ID:
Gene ID:
  • Human(25777) Summary: SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]
  • Mouse(223697) Sad1 and UNC84 domain containing 2
  • Rat(315135) Sad1 and UNC84 domain containing 2
  • dog(481250) Sad1 and UNC84 domain containing 2
  • domestic cat(101096079) Sad1 and UNC84 domain containing 2
  • chicken(418021) Sad1 and UNC84 domain containing 2
  • naked mole-rat(101703115) Sad1 and UNC84 domain containing 2
  • Thale Cress(820242) SAD1/UNC-84 domain-containing protein 2
  • domestic guinea pig(100734538) Sad1 and UNC84 domain containing 2
  • sheep(101106156) Sad1 and UNC84 domain containing 2
  • cow(618392) Sad1 and UNC84 domain containing 2

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esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SUN2,
Species
human