SPAG6
sperm associated antigen 6
Synonyms:
Repro-SA-1, pf16
Species:
Human SPAG6 (9576), Mouse Spag6 (50525), Rat Spag6 (360747), domestic cat SPAG6 (101096155), dog SPAG6 (477978), Zebrafish spag6 (431757), chicken SPAG6 (420505), naked mole-rat Spag6 (101729190), domestic guinea pig Spag6 (100724896), sheep SPAG6 (101103745)
UniProtKB ID:
Gene ID:
- Human(9576) Summary: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
- Mouse(50525) sperm associated antigen 6
- Rat(360747) sperm associated antigen 6
- domestic cat(101096155) sperm associated antigen 6
- dog(477978) sperm associated antigen 6
- Zebrafish(431757) sperm associated antigen 6
- chicken(420505) sperm associated antigen 6
- naked mole-rat(101729190) sperm associated antigen 6
- domestic guinea pig(100724896) sperm associated antigen 6
- sheep(101103745) sperm associated antigen 6
- cow(539424) sperm associated antigen 6
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SPAG6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
western blot
Anti-SPAG6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-SPAG6 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-SPAG6 antibody produced in mouse, clone 2F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-SPAG6 antibody produced in mouse, clone 3E3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
esiRNA
Product Number
Description
Species