MAP3K14
mitogen-activated protein kinase kinase kinase 14
Synonyms:
FTDCR1B, HS, HSNIK, NIK
Species:
Human MAP3K14 (9020), Mouse Map3k14 (53859), Rat Map3k14 (360640), dog MAP3K14 (490926), chicken MAP3K14 (419964), sheep MAP3K14 (101118799), Domestic Rabbit MAP3K14 (100351032), cow MAP3K14 (508367), Horse MAP3K14 (100050140), naked mole-rat Map3k14 (101703313) ...More
UniProtKB ID:
Gene ID:
- Human(9020) Summary: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
- Mouse(53859) mitogen-activated protein kinase kinase kinase 14
- Rat(360640) mitogen-activated protein kinase kinase kinase 14
- dog(490926) mitogen-activated protein kinase kinase kinase 14
- chicken(419964) mitogen-activated protein kinase kinase kinase 14
- sheep(101118799) mitogen-activated protein kinase kinase kinase 14
- Domestic Rabbit(100351032) mitogen-activated protein kinase kinase kinase 14
- cow(508367) mitogen-activated protein kinase kinase kinase 14
- Horse(100050140) mitogen-activated protein kinase kinase kinase 14
- naked mole-rat(101703313) mitogen-activated protein kinase kinase kinase 14
- domestic guinea pig(100719582) mitogen-activated protein kinase kinase kinase 14
- domestic cat(101083468) mitogen-activated protein kinase kinase kinase 14
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MAP3K14 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
proximity ligation assay
western blot
proximity ligation assay
western blot
ANTI-NIK (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-MAP3K14 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, pig, rabbit
Application
western blot
Proteins
Product Number
Description
Species
MAP3K14(NIK) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Species
human