GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Synonyms:
GAD65
Species:
Human GAD2 (2572), Mouse Gad2 (14417), Rat Gad2 (24380), domestic guinea pig Gad2 (100734029), naked mole-rat Gad2 (101698166), Thale Cress GAD2 (842908), sheep GAD2 (101106448), chicken GAD2 (395395), dog GAD2 (487107), domestic cat GAD2 (101082244) ...More
UniProtKB ID:
Gene ID:
- Human(2572) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
- Mouse(14417) glutamic acid decarboxylase 2
- Rat(24380) glutamate decarboxylase 2
- domestic guinea pig(100734029) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- naked mole-rat(101698166) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- Thale Cress(842908) glutamate decarboxylase 2
- sheep(101106448) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- chicken(395395) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- dog(487107) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- domestic cat(101082244) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- cow(512459) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- Zebrafish(550403) glutamate decarboxylase 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GAD2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2736, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-GAD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-GAD65 Antibody, clone 3B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-GAD2/GAD65 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, chimpanzee, human, mouse, rat
Application
ELISA
western blot
western blot
Anti-Glutamate Decarboxylase Antibody, 65 kDa isoform, clone GAD-6, clone GAD-6, Chemicon®, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot