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Merck

GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

Synonyms:
CAE2, ECA2, GEFSP3
Species:
UniProtKB ID:
Gene ID:
  • Human(2566) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14406) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
  • Rat(29709) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Horse(100059571) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • sheep(101118526) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Zebrafish(553402) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • chicken(396289) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • dog(489141) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic cat(100286791) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • cow(282240) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic guinea pig(100723005) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • naked mole-rat(101718598) gamma-aminobutyric acid (GABA) A receptor, gamma 2

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Small Molecule - Agonist

Product Number
Description
Species
γ-Aminobutyric acid, ≥99%,
Species
human, rat
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Lorazepam, United States Pharmacopeia (USP) Reference Standard,
Species
human
Lorazepam, British Pharmacopoeia (BP) Reference Standard,
Species
human
Propofol, British Pharmacopoeia (BP) Reference Standard,
Species
human
Propofol, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Etiocholan-3α-ol-17-one, ,
Species
human, rat
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
2,6-Diisopropylphenol, 97%,
Species
human
Flumazenil, >99% (HPLC), solid,
Species
rat, human
5α-Pregnan-3α-ol-20-one, solid,
Species
human, mouse, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GABRG2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, human, mouse, rat
Application
ELISA
western blot
Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop, Chemicon®, from rabbit,
Species Reactivity
rat
Application
immunoprecipitation (IP)
western blot
Anti-GABAA Receptor (γ2 subunit) (extracellular) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
bovine, human, mouse, rat
Application
western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Etiocholan-3α-ol-17-one, ,
Species
human, rat
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
5α-Pregnan-3α-ol-20-one, solid,
Species
human, mouse, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GABRG2,
Species
human