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Merck

CXCR3

chemokine (C-X-C motif) receptor 3

Synonyms:
CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR
Species:
UniProtKB ID:
Gene ID:
  • Human(2833) Summary: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]
  • Mouse(12766) chemokine (C-X-C motif) receptor 3
  • Rat(84475) chemokine (C-X-C motif) receptor 3
  • domestic cat(101094573) chemokine (C-X-C motif) receptor 3
  • dog(491952) chemokine (C-X-C motif) receptor 3
  • Goat(100860874) chemokine (C-X-C motif) receptor 3
  • cow(497018) chemokine (C-X-C motif) receptor 3
  • sheep(101107671) chemokine (C-X-C motif) receptor 3
  • naked mole-rat(101722797) chemokine (C-X-C motif) receptor 3
  • domestic guinea pig(100735932) chemokine (C-X-C motif) receptor 3

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CXC Chemokine Receptor 3 Antibody, CT domain, Chemicon®, from rabbit,
Species Reactivity
human
Application
immunohistochemistry
Anti-CXCR3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CXCR3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry

immunofluorescence

western blot
Monoclonal Anti-CXCR3 antibody produced in mouse, clone 49801.111, purified immunoglobulin, lyophilized powder,
Species Reactivity
human
Application
flow cytometry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CXCR3,
Species
human