CDK7
cyclin-dependent kinase 7
Synonyms:
CAK1, CDKN7, HCAK, MO15, STK1, p39MO15
Species:
Human CDK7 (1022), Mouse Cdk7 (12572), Rat Cdk7 (171150), domestic guinea pig Cdk7 (100725955), naked mole-rat Cdk7 (101702664), sheep CDK7 (101119934), Horse CDK7 (100049964), Zebrafish cdk7 (405897), dog CDK7 (608441), domestic cat CDK7 (101086781) ...More
UniProtKB ID:
Gene ID:
- Human(1022) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
- Mouse(12572) cyclin-dependent kinase 7
- Rat(171150) cyclin-dependent kinase 7
- domestic guinea pig(100725955) cyclin-dependent kinase 7
- naked mole-rat(101702664) cyclin-dependent kinase 7
- sheep(101119934) cyclin-dependent kinase 7
- Horse(100049964) cyclin-dependent kinase 7
- Zebrafish(405897) cyclin-dependent kinase 7
- dog(608441) cyclin-dependent kinase 7
- domestic cat(101086781) cyclin-dependent kinase 7
- chicken(771294) cyclin-dependent kinase 7
- cow(515462) cyclin-dependent kinase 7
- fruit fly(31441) Cyclin-dependent kinase 7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-CDK7 (pThr170) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CDK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-CDK7 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-CDK7 antibody produced in mouse, clone 1G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-Cdk7/CAK antibody produced in mouse, clone MO-1.1, ascites fluid,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
Cdk7/Cyclin H/MAT1 (CAK complex) Protein, active, 10 µg, Active complex of recombinant full length human Cdk7, containing a C-terminal His6-tag, recombinant full-length human Cyclin H untagged & recombinant full-length human MAT1 containing an N-terminal GST-tag, for use in Kinase Assays.,
Species
human
CDK7/Cyclin H1/MNAT1, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Small Molecule - Substrate
Product Number
Description
Species