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Merck

BMP4

bone morphogenetic protein 4

Synonyms:
BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
Species:
UniProtKB ID:
Gene ID:
  • Human(652) Summary: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq, Jul 2008]
  • Mouse(12159) bone morphogenetic protein 4
  • Rat(25296) bone morphogenetic protein 4
  • dog(490695) bone morphogenetic protein 4
  • Domestic Rabbit(100009569) bone morphogenetic protein 4
  • naked mole-rat(101711207) bone morphogenetic protein 4
  • domestic guinea pig(100733516) bone morphogenetic protein 4
  • sheep(443502) bone morphogenetic protein 4
  • Goat(100860789) bone morphogenetic protein 4
  • cow(407216) bone morphogenetic protein 4
  • Horse(100034048) bone morphogenetic protein 4
  • Zebrafish(30612) bone morphogenetic protein 4
  • chicken(396165) bone morphogenetic protein 4
  • domestic cat(101100311) bone morphogenetic protein 4

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ELISA

Product Number
Description
Species
Human BMP-4 ELISA Kit, for cell and tissue lysates,
Species
human
Human BMP-4 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-BMP4 antibody produced in mouse, clone 10F4B4, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Anti-BMP4 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Bone Morphogenetic Protein 4 human, BMP-4, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
Species
human
BMP-4 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
Bone Morphogenetic Protein 4 human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
Species
human
BMP-4 human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human
BMP-4 mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human BMP4,
Species
human
MISSION® esiRNA, targeting mouse Bmp4,
Species
mouse