3D Cell Culture Techniques
![Human IPSC Derived Colonic Organoids A three dimensional cell culture](/deepweb/assets/sigmaaldrich/marketing/global/images/categories/cell-analysis/3d-cell-culture/human-ipsc-derived-colonic-organoids-400x248/human-ipsc-derived-colonic-organoids-400x248.jpg)
Cells naturally grow and differentiate in 3D environments. Improved 3D cell culture models can more accurately replicate the native tissue environment to provide meaningful scientific conclusions. We offer a broad portfolio of solutions for 3D cell culture including products for supporting spheroid growth, scaffolds, hydrogels, organoids, ULA plates, and other cultureware.
![3D Hydrogels Close-up photo of a transparent, gel-like substance neatly contained within a circular glass dish held by a metal spoon, a sample of a hydrogel](/deepweb/assets/sigmaaldrich/marketing/global/images/categories/cell-analysis/3d-cell-culture/3d-hydrogels-620x384/3d-hydrogels-620x384.jpg)
Hydrogels
Cells embedded in 3D hydrogels can polarize, differentiate and have functional attributes that more closely resemble physiological tissues. Choose naturally derived hydrogels or reconstitute a hydrogel from synthetic materials to develop predictive cellular models.
Scaffolds for 3D Cell Culture
Cells grown on structural scaffolds engineered to mimic the ECM can be powerful, predictive models of physiological processes. Our wide range of advanced 3D cell culture scaffolds includes nanofiber, collagen, polystyrene, and polycaprolactone materials.
![Cells Grown Nanofiber Structural Insert Scanning electron microscope image depicting clusters of microbial cells adhering to a fibrous network, displayed in monochrome for detailed texture analysis.](/deepweb/assets/sigmaaldrich/marketing/global/images/categories/cell-analysis/3d-cell-culture/cells-grown-nanofiber-structural-insert-620x384/cells-grown-nanofiber-structural-insert-620x384.jpg)
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Organoids are in vitro models that closely replicate the complex physiology of native tissues while also being accessible, reproducible, and scalable like traditional culture methods. Choose colon organoids, lung organoid culture systems, and patient-derived organoids from our biobank.
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