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Dipentyl phthalate

Selectophore, ≥99.0%

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About This Item

Empirical Formula (Hill Notation):
C18H26O4
CAS Number:
Molecular Weight:
306.40
Beilstein:
1987323
EC Number:
MDL number:
UNSPSC Code:
26111700
PubChem Substance ID:
NACRES:
NB.61

grade

for ion-selective electrodes

Quality Level

product line

Selectophore

Assay

≥99.0% (GC)
≥99.0%

form

liquid

refractive index

n20/D 1.490

density

1.025 g/mL at 20 °C (lit.)

SMILES string

CCCCCOC(=O)c1ccccc1C(=O)OCCCCC

InChI

1S/C18H26O4/c1-3-5-9-13-21-17(19)15-11-7-8-12-16(15)18(20)22-14-10-6-4-2/h7-8,11-12H,3-6,9-10,13-14H2,1-2H3

InChI key

IPKKHRVROFYTEK-UHFFFAOYSA-N

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General description

Dipentyl phthalate (DPeP) belongs to phthalate group, and is a dialkyl or aryl/alkyl diesters of phthalic acid. It may be prepared from phthalic anhydride along with n-pentanol.
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Application


  • Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats: Dipentyl phthalate′s structural similarities to DINP underpin studies on phthalate exposure′s impacts on male reproductive health, providing insights into potential risks and mechanisms of toxicity in developmental stages (Earl Gray L Jr, 2023).

  • Exposure to dipentyl phthalate in utero disrupts the adrenal cortex function of adult male rats by inhibiting SIRT1/PGC-1α and inducing AMPK phosphorylation: This study uses dipentyl phthalate to examine the adverse effects of phthalate exposure on adrenal gland function, contributing to a deeper understanding of metabolic disruptions (Chen et al., 2023).

  • Determination of 15 phthalic acid esters based on GC-MS/MS coupled with modified QuEChERS in edible oils: This research demonstrates the utility of dipentyl phthalate in method development for detecting phthalates in food matrices, enhancing food safety assessments (Wang et al., 2022).

  • Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development: Dipentyl phthalate is investigated for its role in developmental toxicity, aiding in the construction of models predicting reproductive health effects from chemical exposures (Palermo et al., 2021).

Other Notes

Plasticizer for PVC membrane electrodes

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

244.4 °F - closed cup

Flash Point(C)

118 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M.M. Khalil
Analytical Letters, 26, 2071-2071 (1993)
Potassium-selective electrodes based on macrocyclic polyethers: The effect of structure of the neutral carrier on selectivity.
Petranek, J., and O. Ryba.
Analytica Chimica Acta, 72.2, 375-380 (1974)
S. Nomura
Analyst, 120, 503-503 (1995)
T Granholm et al.
Journal of reproductive immunology, 21(1), 1-14 (1992-01-01)
Phthalate esters (PAE) are plasticizers in polyvinyl chloride plastics used, for example, in package material for medical solutions. PAE exposure is associated with testicular damage that primarily affects Sertoli cells, and is concomitant with leukocyte infiltration into the testicular interstitium.
P M Foster et al.
Toxicology letters, 15(2-3), 265-271 (1983-02-01)
Treatment of young male rats with dipentyl phthalate (DPP) produced significant decreases in testicular cytochrome P-450, cytochrome P-450 dependent microsomal steroidogenic enzymes (17 alpha-hydroxylase, 17-20 lyase) and in the maximal binding of a natural substrate (progesterone) to testis microsomes. No

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