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Key Documents

444270

Sigma-Aldrich

MMP-7, Active, Human, Recombinant, E. coli

Synonym(s):

Matrilysin, rhMMP-7, PUMP-1

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About This Item

Enzyme Commission number:
UNSPSC Code:
12352202
NACRES:
NA.77

form

liquid

Quality Level

specific activity

≥3000 units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−70°C

General description

Recombinant, human MMP-7 expressed in E. coli. MMP-7, the smallest member of the matrix metalloproteinase family that can degrade a wide range of gelatins, proteoglycans, and glycoproteins of the matrix and can activate several other MMPs.
Recombinant, human MMP-7 expressed in E. coli. MMP-7 is the smallest member of the matrix metalloproteinase family that can degrade a wide range of gelatins, proteoglycans, and glycoproteins of the matrix and activate several other MMPs.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of enzyme that will digest 1.0 µg AZOCOLL Substrate (Cat. No. 194933) per min at 37°C, pH 7.5.

Physical form

In 150 mM NaCl, 10 mM HEPES, 5 mM CaCl₂, pH 7.4.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Kivelä-Rajamäki, M., et al. 2003. J. Periodont. Res.38, 583.
Woessner, J.F. 1995. Methods Enzymol. 248, 485.
Crabbe, T., et al. 1992. Biochemistry 31, 8500.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Scott A Johnson et al.
Methods in molecular medicine, 105, 95-106 (2004-10-20)
The primary sites of hematopoiesis change during murine ontogeny. The first blood cells emerge in two waves in the yolk sac; primitive erythroblasts, megakaryocytes, and macrophages emerge on embryonic d (E) 7.0, whereas definitive progenitor cells appear as clusters within
Katherine Conant et al.
Journal of neuroinflammation, 14(1), 56-56 (2017-03-18)
Matrix metalloproteinases (MMPs) are a family of enzymes that are typically released from intracellular stores to act on specific extracellular substrates. MMP expression and activity can be increased in a neuronal activity-dependent manner, and further increased in response to tissue

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