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Synthesis of deuterium-labelled isotopomer of deferasirox.

Journal of labelled compounds & radiopharmaceuticals (2015-02-19)
Freddy H Havaldar, Bhushan Vasant Dabholkar, Ganesh Baban Mule, Suhas Kulkarni
RÉSUMÉ

A d4 -labeled isotopomer of deferasirox was synthesized as internal standard for use in a LC/mass spectroscopy (MS)/MS method developed for the simultaneous quantitative determination of deferasirox in human serum. d4 -deferasirox was synthesized from d8 -toluene.

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Sigma-Aldrich
Toluène-d8, 99.6 atom % D
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