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Merck

Synthetic approaches towards structurally diverse gamma-butyrolactone natural-product-like compounds.

Current opinion in chemical biology (2005-06-09)
Michael Seitz, Oliver Reiser
RÉSUMÉ

Natural products containing a gamma-butyrolactone ring are abundant in nature; however, few general synthetic approaches to their stereoselective synthesis with broad structural variety are known. In this article, recent developments towards mono- and polycyclic gamma-butyrolactone natural products and analogs are discussed. A special focus is given to asymmetric methods applying transition metal or organocatalysts that allow not only the efficient introduction of a broad variety of functional groups but ideally also the flexible construction of various natural-product-like, polycyclic scaffolds from common precursors.

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Description du produit

Sigma-Aldrich
γ-Butyrolactone, ReagentPlus®, ≥99%
Sigma-Aldrich
γ-Butyrolactone, ≥98%, FCC, FG
Supelco
γ-Butyrolactone, analytical standard
Sigma-Aldrich
γ-Butyrolactone, SAJ first grade, ≥99.5%