- Palladium-catalyzed cascade cyclization of ynamides to azabicycles.
Palladium-catalyzed cascade cyclization of ynamides to azabicycles.
Chemistry (Weinheim an der Bergstrasse, Germany) (2011-11-25)
Rebecca L Greenaway, Craig D Campbell, Oliver T Holton, C Adam Russell, Edward A Anderson
PMID22113952
RÉSUMÉ
Cascade reactions: A modular assembly of azabicycles by using a cascade cyclization/Suzuki coupling/6π-electrocyclization of bromoenynamides is reported. The reaction offers a wide substituent scope on the bicyclic aminodiene products, which can be selectively oxidized as a general approach to aromatic azabicycles.
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