SML0309

Sodium phenylbutyrate

≥98% (HPLC)

• Synonyme(s) : 4-PBA, 4-Phenylbutyric acid, 4-phenylbutyrate, Buphenyl, Sodium 4-phenylbutyrate, TriButyrate
• Formule empirique (notation de Hill): C₁₀H₁₁NaO₂
• Numéro CAS: 1716-12-7
• Poids moléculaire : 186.18
• Numéro MDL: MFCD00800247
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825314
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: H₂O: ≥5 mg/mL
• Température de stockage: room temp
• Chaîne SMILES: [Na+].[O-]C(=O)CCCc1ccccc1
• InChI: 1S/C10H12O2.Na/c11-10(12)8-4-7-9-5-2-1-3-6-9;/h1-3,5-6H,4,7-8H2,(H,11,12);/q;+1/p-1
• Clé InChI: VPZRWNZGLKXFOE-UHFFFAOYSA-M

Description

Description générale

Sodium phenylbutyrate stimulates urinary nitrogen excretion. It is a prodrug, which undergoes β-oxidation to phenylacetate. Sodium phenylbutyrate is used to treat urea cycle disorder. It might be associated with menstrual dysfunction, amenorrhea and painful mucositis of the esophagus and stomach.

Application

Sodium phenylbutyrate has been used as an endoplasmic reticulum (ER) stress inhibitor to study the role of ER stress in the expression of betatrophin.

Actions biochimiques/physiologiques

Sodium phenylbutyrate is a histone deacetylase inhibitor.

Caractéristiques et avantages

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable