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P9625

Sigma-Aldrich

Phenazine methosulfate

powder, electron acceptor

Synonyme(s) :

5-Methylphenazinium methyl sulfate, N-Methylphenazonium methyl sulfate, PMS

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About This Item

Formule linéaire :
C13H11N2 · CH3SO4
Numéro CAS:
299-11-6
Poids moléculaire :
306.34
Numéro Beilstein :
3898869
Numéro CE :
206-072-1
Numéro MDL:
MFCD00011923
Code UNSPSC :
12352200
ID de substance PubChem :
24899045
Nomenclature NACRES :
NA.77

product name

Phenazine methosulfate,

Forme

powder

λ

0.01 g/L in H2O, 1 cm path

Absorption UV

λ: 387.5 nm Amax

Spectre d'activité de l'antibiotique

fungi

Mode d’action

DNA synthesis | interferes
cell membrane | interferes

Température de stockage

−20°C

Chaîne SMILES 

COS([O-])(=O)=O.C[n+]1c2ccccc2nc3ccccc13

InChI

1S/C13H11N2.CH4O4S/c1-15-12-8-4-2-6-10(12)14-11-7-3-5-9-13(11)15;1-5-6(2,3)4/h2-9H,1H3;1H3,(H,2,3,4)/q+1;/p-1

Clé InChI

RXGJTUSBYWCRBK-UHFFFAOYSA-M

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Description générale

Phenazines are heterocyclic compounds produced as secondary metabolites by bacteria.

Application

Phenazine methosulfate is used with ascorbic acid to determine nitric oxide reductase activity.
Phenazine methosulfate has been used:
  • as a component of succinate dehydrogenase enzyme substrate solution
  • to induce superoxide radical generation in red blood cell suspensions and to study its influence on RBC deformability
  • as a component of complex II histochemistry media

Actions biochimiques/physiologiques

Phenazine m ethosulfate (PMS) acts as a good electron acceptor. PMS is reduced non-enzymatically by (nicotinamide adenine dinucleotide) NADH and (nicotinamide adenine dinucleotide phosphate) NADPH.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Handbook on Clostridia, , pages=, 84-84 (2005)
Ludmila Yarmolinsky et al.
Rejuvenation research, 22(4), 282-288 (2018-10-26)
Crude ethanolic extracts from Phlomis viscosa Poiret leaves from the Judea region (Israel) are renowned for their remarkable geroprotective properties: anti-inflammatory, anti-diabetic, and anti-cancer. A phytochemical investigation carried out in this study revealed that the tested plant might belong to
Ángela Inmaculada López-Lorente et al.
Materials science & engineering. C, Materials for biological applications, 103, 109805-109805 (2019-07-28)
In recent years, both nanotechnology and the use of nanomaterials have been growing in fields as diverse as biomedicine, food or electronics. Particularly metal nanoparticles, such as gold nanoparticles (AuNPs), are being widely studied with different applications, for example as
Junji Zhang et al.
Nature communications, 8(1), 987-987 (2017-10-19)
Development of powerful fluorescence imaging probes and techniques sets the basis for the spatiotemporal tracking of cells at different physiological and pathological stages. While current imaging approaches rely on passive probe-analyte interactions, here we develop photochromic fluorescent glycoprobes capable of
Duong Luong et al.
Materials science & engineering. C, Materials for biological applications, 103, 109759-109759 (2019-07-28)
Transition metals (TM) are essential microelements with various biological functions demanded in tissue regeneration applications. Little is known about therapeutic potential of TM within soft hydrogel biomaterials. The soluble divalent TM, such as Zn, Cu, Mn and Co, were stably
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