P4247

Anti-Potassium Channel K_v1.3 (extracellular)−FITC antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• Synonyme(s) : Anti-Kcna3, Anti-Voltage-gated Potassium Channel K_V1.3
• Numéro MDL: MFCD06798515
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 200
• Conjugué: FITC conjugate
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: lyophilized powder
• Espèces réactives: rat, human, mouse
• Technique(s): flow cytometry: 0.5-5 μg/test using Jurkat T-cells; western blot: 1:200-1:500 using rat brain membranes
• Numéro d'accès UniProt: P22001
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... KCNA3(3738) ; mouse ... Kcna3(16491) ; rat ... Kcna3(29731)

Description

Description générale

The (K⁺) channel family has been sub-grouped in to 2 TM, 4 TM and 6 TM (K⁺) channels based on the number of transmembrane domains. The voltage-gated Potassium or (Kv) channels belong to the 6 TM (K⁺) channel family and are expressed mainly in hematopoietic cells such as T and B lymphocytes, macrophages and natural killer cells. (Kv)1.3 facilitates cell proliferation and can also regulate the immune system. Genetic alterations in (Kv) 1.3 lead to epilepsy, episodic ataxia/myokymia, and episodic cardiac arrhythmia (the long QT syndrome). Anti-potassium channel (Kv) 1.3 (extracellular)−FITC antibody can be used for western blotting of rat brain membranes. Rabbit anti- potassium channel (Kv) 1.3 (extracellular) antibodies reacts specifically with rat and human (Kv) 1.3.

Immunogène

synthetic peptide corresponding to residues 211-224 of human K_V1.3. Rat and mouse are 12/14 residues identical.

Application

Anti-potassium channel (Kv) 1.3 (extracellular)−FITC antibody can be used in immunoblotting and flow cytometry.

Forme physique

Lyophilized from phosphate buffered saline, pH 7.4, 1% bovine serum albumin, 0.05% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable