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Key Documents

F7884

Sigma-Aldrich

Anti-Dog IgG (whole molecule)–FITC antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Rabbit Anti-Dog IgG (whole molecule)–Fluorescein isothiocyanate

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

rabbit

Conjugué

FITC conjugate

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Conditions de stockage

protect from light

Technique(s)

direct immunofluorescence: 1:32

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

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Description générale

IgG (Immunoglobulin G) antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Rabbit anti-dog IgG is isolated by affinity isolation and conjugated to Fluorescein Isothiocyanate (FITC).
The variable region of IgG antibody is specific to antigens and is highly conserved. IgG has four subclasses- IgG1, IgG2a, IgG2b and IgG2c.

Spécificité

Anti-Dog IgG (whole molecule)-FITC antibody is specific for dog IgG subclasses.

Immunogène

Purified dog IgG

Application

Anti-Dog IgG (whole molecule)-FITC antibody may be used for direct immunofluorescence using dog peripheral blood lymphocytes at a minimum working dilution of 1:32.

Actions biochimiques/physiologiques

IgG (Immunoglobulin G) antibody provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. IgG antibody has its function similar to IgM antibody in complement system activation. IgG participates in hypersensitivity type II and type III. It helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Stockage et stabilité

For continuous use, store at 2-8 °C for up to one month.
For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing, or storage in "frost-free" freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Hanna D Bremer et al.
Scientific reports, 8(1), 4852-4852 (2018-03-21)
Dogs can spontaneously develop complex systemic autoimmune disorders, with similarities to human autoimmune disease. Autoantibodies directed at self-antigens are a key feature of these autoimmune diseases. Here we report the identification of interleukin enhancer-binding factors 2 and 3 (ILF2 and
Vanessa Figueredo Pereira et al.
Revista da Sociedade Brasileira de Medicina Tropical, 49(1), 104-106 (2016-05-11)
Conjunctival swab PCR was evaluated as a tool to diagnose visceral leishmaniasis in dogs. Conjunctival swab PCR was compared to indirect immunofluorescence antibody test and blood PCR. Indirect immunofluorescence was significantly correlated with conjunctival swab PCR (p < 0.05), but
Gisele Vaz Aguirre Samoel et al.
Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria, 33(1), e013723-e013723 (2023-12-21)
Bovine trypanosomosis, caused by Trypanosoma vivax, is a disease that originated in Africa and currently affects cattle in several South American countries, including almost all Brazilian states. Despite the reports on T. vivax infection in southern Brazil, data on its
Comparative evaluation of the DPP? CVL rapid test for canine serodiagnosis in area of visceral leishmaniasis.
Laurenti M D, et al.
Veterinary Parasitology, 205(3-4) (2014)
Nataša Knap et al.
Viruses, 12(7) (2020-07-09)
West Nile virus (WNV) is a flavivirus transmitted by mosquitoes. Birds are the reservoir for the virus; humans, horses and other mammals are dead-end hosts. Infections caused by WNV in humans can vary from asymptomatic infections to West Nile fever

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