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D2600000

Diphenhydramine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride, N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride

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About This Item

Formule empirique (notation de Hill):
C17H21NO · HCl
Numéro CAS:
147-24-0
Poids moléculaire :
291.82
Numéro MDL:
MFCD00012479
Code UNSPSC :
41116107
ID de substance PubChem :
329798746
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

diphenhydramine

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

Cl[H].CN(C)CCOC(c1ccccc1)c2ccccc2

InChI

1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H

Clé InChI

PCHPORCSPXIHLZ-UHFFFAOYSA-N

Informations sur le gène

human ... HRH1(3269)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Diphenhydramine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1015

Diphenhydramine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1218005

Diphenhydramine hydrochloride, United States Pharmacopeia (USP) Reference Standard

Y0000135

Diphenhydramine impurity A, European Pharmacopoeia (EP) Reference Standard

1218016

Diphenhydramine Related Compound A, United States Pharmacopeia (USP) Reference Standard

1217909

Diphenhydramine citrate, United States Pharmacopeia (USP) Reference Standard

1424209

Methylbenzhydrol, United States Pharmacopeia (USP) Reference Standard

38682

Diphenhydramine N-oxide hydrochloride, pharmaceutical impurity standard

1051602

Benzhydrol, United States Pharmacopeia (USP) Reference Standard

1218050

Diphenhydramine N-oxide, United States Pharmacopeia (USP) Reference Standard

1218027

Diphenhydramine Related Compound B, United States Pharmacopeia (USP) Reference Standard

PHR1899

Diphenhydramine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1897

Diphenhydramine Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

BP896

Diphenhydramine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR1898

Diphenhydramine N-Oxide Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1993

Diphenhydramine Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2071

Benzhydrol, Pharmaceutical Secondary Standard; Certified Reference Material

BP1119

Diphenylmethanol, British Pharmacopoeia (BP) Reference Standard

PHR2268

Diphenhydramine Citrate, pharmaceutical secondary standard, certified reference material

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Conseils de prudence

P301 + P312 + P330

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Sigma-Aldrich

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A D Rollstin et al.
Clinical toxicology (Philadelphia, Pa.), 51(1), 50-53 (2012-12-01)
There are few reports of acetaminophen overdose in hypothermic patients and even fewer reports describing profound hypothermia. The kinetics, risk of hepatotoxicity, and the possible dose adjustments to N-acetylcysteine (NAC) therapy are not known in this setting. A 37-year-old female
Eugene W Schwilke et al.
Journal of forensic sciences, 51(5), 1191-1198 (2006-10-05)
We have previously reported on patterns of drug and alcohol use in fatally injured drivers in Washington State. Here we revisit that population to examine how drug use patterns have changed in the intervening 9 years. Blood and serum specimens
Edward Topp et al.
The Science of the total environment, 439, 136-140 (2012-10-16)
The widely used antihistamine diphenhydramine is present in municipal biosolids, and is detected in runoff from agricultural land fertilized with biosolids. In the present study the kinetics and major pathways of diphenhydramine dissipation in a loam, sandy loam, and clay
Don W Coulter et al.
Anti-cancer drugs, 24(4), 415-421 (2013-01-19)
A pediatric study has established a maximum tolerated dose (MTD) for temsirolimus (Tem) of more than 150 mg/m intravenously/week. A phase I trial was conducted to establish the MTD for Tem in combination with valproic acid (VPA) in children and
Mohammed Maniruzzaman et al.
International journal of pharmaceutics, 443(1-2), 199-208 (2012-12-25)
The purpose of the study was to investigate and identify the interactions within solid dispersions of cationic drugs and anionic polymers processed by hot-melt extrusion (HME) technique. Propranolol HCl (PRP) and diphenhydramine HCl (DPD) were used as model cationic active
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