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BP809

Cisplatin

British Pharmacopoeia (BP) Reference Standard

Synonyme(s) :

cis-Diammineplatinum(II) dichloride, cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin

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About This Item

Formule linéaire :
Pt(NH3)2Cl2
Numéro CAS:
15663-27-1
Poids moléculaire :
300.05
Numéro CE :
239-733-8
Numéro MDL:
MFCD00011623
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

cisplatin

Forme

solid

Durée de conservation

limited shelf life, expiry date on the label

Fabricant/nom de marque

BP

Pf

270 °C (lit.)

Application(s)

pharmaceutical
pharmaceutical small molecule

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

N.N.Cl[Pt]Cl

InChI

1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

Clé InChI

LXZZYRPGZAFOLE-UHFFFAOYSA-L

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cisplatin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Cisplatin Injection

    • Actions biochimiques/physiologiques

    Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.

    Conditionnement

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Autres remarques

    Sales restrictions may apply.

    Produit(s) apparenté(s)

    Réf. du produit
    Description
    Tarif

    C2210000

    Cisplatin, European Pharmacopoeia (EP) Reference Standard

    Y0001019

    Cisplatin impurity B, European Pharmacopoeia (EP) Reference Standard

    Y0001018

    Cisplatin impurity A, European Pharmacopoeia (EP) Reference Standard

    1551300

    Potassium Trichloroammineplatinate, United States Pharmacopeia (USP) Reference Standard

    1672803

    Transplatin, United States Pharmacopeia (USP) Reference Standard

    1134357

    Cisplatin, United States Pharmacopeia (USP) Reference Standard

    PHR1624

    Cisplatin, Pharmaceutical Secondary Standard; Certified Reference Material

    BP510

    Potassium trichloroammineplatinate, British Pharmacopoeia (BP) Reference Standard

    BP544

    Transplatin, British Pharmacopoeia (BP) Reference Standard

    PHR3252

    Transplatin, pharmaceutical secondary standard, certified reference material

    Pictogrammes

    Skull and crossbonesHealth hazard
    GHS06,GHS08

    Mention d'avertissement

    Danger

    Classification des risques

    Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

    Organes cibles

    Respiratory system

    Code de la classe de stockage

    6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

    Classe de danger pour l'eau (WGK)

    WGK 3

    Point d'éclair (°F)

    Not applicable

    Point d'éclair (°C)

    Not applicable

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    Certificats d'analyse (COA)

    Lot/Batch Number

    Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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    Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

    Consulter la Bibliothèque de documents

    Shihong Ma et al.
    Journal of cellular biochemistry, 121(5-6), 3256-3265 (2020-01-07)
    Aberrant activation of the Hedgehog (Hh)/Gli pathway contributes to the tumorigenesis of several human cancers, including ovarian cancers. We investigated the function of SMO on cell growth, drug resistance, and invasive ability in A2780/DDP cells. Moreover, we also tested the
    Xiaochen Wang et al.
    Stem cells international, 2020, 8877577-8877577 (2020-09-05)
    Esophageal squamous cell carcinoma (ESCC) is a frequent malignant tumor with low 5-year overall survival. Targeting ESCC tumor-initiating cells (TICs) may provide a new research avenue to achieve better therapeutic effects of ESCC. However, the identity and characteristics of ESCC
    Ruiqian Li et al.
    International urology and nephrology, 52(1), 187-196 (2019-12-13)
    Cisplatin could result in a wide range of kidney injuries. During the pathogenetic process, the excessive generation of reactive oxygen species (ROS) induced by cisplatin has been regarded as the initial and critical role, by which DNA damage and cell
    Teng Wang et al.
    Biochimica et biophysica acta. Molecular cell research, 1867(12), 118833-118833 (2020-08-30)
    Epithelial-mesenchymal transition (EMT) is considered as the key mechanism involved in cancer metastasis. Several studies showed that various cell membrane calcium channels play different roles in cancer metastasis. In the present study, the potential role of ATPase plasma membrane Ca2+
    Tengfei Liu et al.
    Nature communications, 11(1), 2788-2788 (2020-06-05)
    Oxidative stress is associated with many acute and chronic inflammatory diseases, yet limited treatment is currently available clinically. The development of enzyme-mimicking nanomaterials (nanozymes) with good reactive oxygen species (ROS) scavenging ability and biocompatibility is a promising way for the
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