41131
Mettler-Toledo Calibration substance ME 51143091, Saccharin
traceable to primary standards (LGC)
Synonyme(s) :
Saccharin, 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide, 2-Sulfobenzoic acid imide, o-Benzoic sulfimide
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About This Item
Formule empirique (notation de Hill):
C7H5NO3S
Numéro CAS:
Poids moléculaire :
183.18
Numéro Beilstein :
6888
Numéro CE :
Numéro MDL:
Code UNSPSC :
20121904
ID de substance PubChem :
Nomenclature NACRES :
NA.24
Produits recommandés
Qualité
analytical standard
traceable to primary standards (LGC)
Niveau de qualité
Durée de conservation
limited shelf life, expiry date on the label
Pf
226-229 °C (lit.)
Application(s)
food and beverages
pharmaceutical
Format
neat
Chaîne SMILES
O=C1NS(=O)(=O)c2ccccc12
InChI
1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
Clé InChI
CVHZOJJKTDOEJC-UHFFFAOYSA-N
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Catégories apparentées
Description générale
Mettler-Toledo calibration substance ME 51143091, saccharin is an analytical standard, designed for the routine calibration of Mettler-Toledo melting point instrument. Its value is an average of 6 to 12 measurements with a Mettler-Toledo MP90 Excellence instrument that is calibrated against primary standards. The melting point is validated by Capillary method as per European Pharmacopeia (2.2.14.)
Application
Saccharin Mettler-Toledo calibration substance ME 51143091 is a melting point calibration standard used to calibrate Mettler-Toledo mp instruments.
Actions biochimiques/physiologiques
A sweet tastant for mammals. A glycerol taste receptor binding site specific for glucose has been proposed in drosophila.
Caractéristiques et avantages
- Traceable to a primary standard from LGC, London
- Melting point evaluation conducted in both thermodynamic and pharmacopeia modes for physically correct and heating rate dependent melting point determinations, respectively
- Available with certificates of analysis and safety data sheet
- A product of analytical standard grade to help meet the QC/QA requirements of melting point determination
- Uncertainty of measurement up to ± 0.3 °C
Informations légales
Mettler-Toledo is a registered trademark of Mettler-Toledo, Inc.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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In a recent study, intragastric (IG) self-infusion of 16% glucose stimulated 1-h intake and conditioned a preference for a flavored saccharin solution in C57BL/6J mice (Zukerman et al., 2011). Experiment 1 of the present study presents a concentration-response analysis of
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Cocrystals constitute an important class of pharmaceutical solids for their remarkable ability to modulate solubility and pH dependence of water insoluble drugs. Here we show how cocrystals of indomethacin-saccharin (IND-SAC) and carbamazepine-saccharin (CBZ-SAC) enhance solubility and impart a pH-sensitivity different
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A process for the regioselective amination of unsymmetrical 3,5-substituted pyridine N-oxides has been developed utilizing cheap, readily available saccharin as an ammonium surrogate. High conversions of the corresponding saccharin adducts have been achieved under mild reaction conditions. In situ deprotection
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