8.52124

Fmoc-Lys(Alloc)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem^®

• Synonyme(s) : Fmoc-Lys(Alloc)-OH
• Formule empirique (notation de Hill): C₂₅H₂₈N₂O₆
• Numéro CAS: 146982-27-6
• Poids moléculaire : 452.50
• Numéro MDL: MFCD00190872
• Code UNSPSC : 12352209
• Nomenclature NACRES : NA.22

Propriétés

• product name: Fmoc-Lys(Alloc)-OH, Novabiochem^®
• Niveau de qualité: 200
• Gamme de produits: Novabiochem^®
• Pureté: ≥96.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Forme: powder
• Capacité de réaction: reaction type: Fmoc solid-phase peptide synthesis
• Fabricant/nom de marque: Novabiochem^®
• Pf: 87-91 °C
• Application(s): peptide synthesis
• Groupe fonctionnel: amine
• Température de stockage: 2-30°C
• InChI: 1S/C25H28N2O6/c1-2-15-32-24(30)26-14-8-7-13-22(23(28)29)27-25(31)33-16-21-19-11-5-3-9-17(19)18-10-4-6-12-20(18)21/h2-6,9-12,21-22H,1,7-8,13-16H2,(H,26,30)(H,27,31)(H,28,29)/t22-/m0/s1
• Clé InChI: OJBNDXHENJDCBA-QFIPXVFZSA-N

Description

Description générale

Orthogonally-protected building block for the synthesis of branched and cyclic peptides and peptides modified at the Lys side chain by Fmoc SPPS. The Alloc group can be selectively removed in the presence of standard Fmoc- and t-butyl-based protecting groups by treatment with Pd(Ph₃P)₄/CHCl₃/AcOH/NMM.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS

Liaison

Replaces: 04-12-1305

Remarque sur l'analyse

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Optical rotation α 25/D (c=1 in DMF): -13.5 - -11.0 °
Purity (TLC(157A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 96.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informations légales

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable