444218

MMP-3 Inhibitor I

The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• Synonyme(s) : MMP-3 Inhibitor I, Ac-RCGVPD-NH₂, Stromelysin-1 Inhibitor
• Formule empirique (notation de Hill): C₂₇H₄₆N₁₀O₉S
• Poids moléculaire : 686.78
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥90% (HPLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated (hygroscopic)
• Couleur: white
• Solubilité: water: 1 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

Inhibits matrix metalloproteinase-3 (stromelysin) (IC₅₀ = 5 µM). The inhibitor is based on a segment from the conserved region of the NH₂-terminal propeptide domain.

Inhibits the matrix metalloproteinase MMP-3 (IC₅₀ = 5 µM).

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
MMP-3

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 5 µM against MMP-3

Avertissement

Toxicity: Standard Handling (A)

Séquence

Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂

Forme physique

Supplied as a trifluroacetate salt.

Reconstitution

Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.

Autres remarques

Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable