12-373
CHKtide (CHK1/CHK2 substrate peptide)
CHKtide (CHK1/CHK2 substrate peptide) primarily used in Kinase Assays.
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About This Item
Code UNSPSC :
12352200
eCl@ss :
32160405
Nomenclature NACRES :
NA.41
Produits recommandés
Niveau de qualité
Fabricant/nom de marque
Upstate®
Technique(s)
activity assay: suitable (kinase)
Numéro d'accès NCBI
Conditions d'expédition
wet ice
Informations sur le gène
human ... CHEK1(1111)
Actions biochimiques/physiologiques
Protein Target: CHK
Target Sub-Family: CAMK
Qualité
Routinely evaluated by Protein Kinase Assay as a substrate for the active CHK1 (Catalog #14-346) and CHK2 (Catalog #14-347) kinases.
Forme physique
Lyophilized powder
Stockage et stabilité
Lyophilized: 2 years at 4°C; Rehydrated: 6 months at -20°C.
Informations légales
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Hidemasa Oh et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(9), 5378-5383 (2003-04-19)
The "postmitotic" phenotype in adult cardiac muscle exhibits similarities to replicative senescence more generally and constitutes a barrier to effective restorative growth in heart disease. Telomere dysfunction is implicated in senescence and apoptotic signaling but its potential role in heart
B Furnari et al.
Science (New York, N.Y.), 277(5331), 1495-1497 (1997-09-05)
Arrest of the cell cycle at the G2 checkpoint, induced by DNA damage, requires inhibitory phosphorylation of the kinase Cdc2 in both fission yeast and human cells. The kinase Wee1 and the phosphatase Cdc25, which regulate Cdc2 phosphorylation, were evaluated
Y Sanchez et al.
Science (New York, N.Y.), 277(5331), 1497-1501 (1997-09-05)
In response to DNA damage, mammalian cells prevent cell cycle progression through the control of critical cell cycle regulators. A human gene was identified that encodes the protein Chk1, a homolog of the Schizosaccharomyces pombe Chk1 protein kinase, which is
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