1.07069

Phloroglucinol

(1,3,5-trihydroxybenzene) for analysis

• Synonyme(s) : Phloroglucinol, 1,3,5-Trihydroxybenzene
• Formule linéaire : C₆H₃-1,3,5-(OH)₃
• Numéro CAS: 108-73-6
• Poids moléculaire : 126.11
• Numéro MDL: MFCD00002286
• Code UNSPSC : 12352104
• Numéro de classement CE : 203-611-2
• Nomenclature NACRES : SE.11

Propriétés

• Niveau de qualité: 100
• Pureté: ≥99.0% (GC)
• Forme: crystals; fine powder
• Puissance: 4000 mg/kg LD₅₀, oral (Rat)
• Pf: 217-220 °C
• Solubilité: 10 g/L
• Masse volumique apparente: 560 kg/m³
• Température de stockage: 15-25°C
• InChI: 1S/C6H6O3/c7-4-1-5(8)3-6(9)2-4/h1-3,7-9H
• Clé InChI: QCDYQQDYXPDABM-UHFFFAOYSA-N

Description

Application

• Biomimetic Synthesis and Chemical Proteomics Reveal the Mechanism of Action and Functional Targets of Phloroglucinol Meroterpenoids.: This study explores the synthesis and mechanisms of phloroglucinol-based compounds, focusing on their biological activity and potential therapeutic applications. It highlights the use of chemical proteomics to identify functional targets, contributing to the understanding of phloroglucinol′s role in medicinal chemistry (Bracken et al., 2024).


• Clinical efficacy and metabolomics study of Wendan Decoction in the treatment of phlegm-dampness obstructive sleep apnea-hypopnea syndrome with type 2 diabetes mellitus.: This research investigates the clinical effects and metabolic pathways influenced by Wendan Decoction, which includes phloroglucinol as a component. The study uses metabolomics to elucidate the biochemical interactions and therapeutic effects in patients with sleep apnea and diabetes (Zhou et al., 2023).


• Metabolomics characterizes early metabolic changes and markers of tolerant Eucalyptus ssp. clones against drought stress.: This paper employs metabolomics to study drought tolerance in Eucalyptus clones, identifying early metabolic changes involving phloroglucinol derivatives. The findings enhance the understanding of plant resilience mechanisms under stress conditions (Noleto-Dias et al., 2023).


• Phloroglucinol and Its Derivatives: Antimicrobial Properties toward Microbial Pathogens.: This review compiles data on the antimicrobial activities of phloroglucinol and its derivatives, emphasizing their potential as bioactive agents in combating various microbial pathogens. The study covers the spectrum of their efficacy and possible applications in microbial control (Khan et al., 2022).


• Anti-Inflammatory Markers of Hops Cultivars (Humulus lupulus L.) Evaluated by Untargeted Metabolomics Strategy.: This research identifies anti-inflammatory compounds in hops, including phloroglucinol derivatives, using an untargeted metabolomics approach. The study provides insights into the biochemical basis of the anti-inflammatory properties of hops (Nicacio et al., 2022).

Remarque sur l'analyse

Color (visual): white to yellowish
Appearance of substance (visual): fine powder or crystals
Assay (GC, area%): ≥ 99.0 % (a/a)
Loss on Drying (105°C): ≤ 1.0 %
Sulfated ash: ≤ 0.1 %
Diresorcinol: passes test
Identity (IR): passes test

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H317,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable