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Key Documents

09-066

Sigma-Aldrich

Anti-ASPM Antibody

from rabbit, purified by affinity chromatography

Synonyme(s) :

Abnormal spindle protein homolog, Asp homolog, asp (abnormal spindle) homolog, microcephaly associated (Drosophila), asp (abnormal spindle)-like, microcephaly associated, asp (abnormal spindle)-like, microcephaly associated (Drosophila), microcephaly, pr

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

rat, human

Réactivité de l'espèce (prédite par homologie)

chimpanzee, primate

Technique(s)

ELISA: suitable
immunohistochemistry: suitable

Numéro d'accès NCBI

NP_060606

Numéro d'accès UniProt

Q8IZT6

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ASPM(259266)

Description générale

The ASPM gene is the human ortholog of the Drosophila melanogaster ′abnormal spindle′ gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts (Bond et al., 2002 [PubMed 12355089]). The mouse gene ASPM is expressed specifically in the primary sites of prenatal cerebral cortical neurogenesis.

Spécificité

This antibody recognizes ASPM.

Immunogène

KLH-conjugated linear peptide corresponding to human ASPM.

Application

Anti-ASPM Antibody detects level of ASPM & has been published & validated for use in IH, ELISA.
ELISA: Tested in direct ELISA against the ASPM immunogen.
Research Category
Signaling
Research Sub Category
Cell Cycle, DNA Replication & Repair

Qualité

Immunohistochemistry Analysis: 1:300 dilution of this antibody detected ASPM in human ductal carcinoma tissue.

Description de la cible

218, 95, 75 kDa Observed UniProtKB/Swiss-Prot entry Q8IZT6 describes 2 isoforms produced by alternative splicing: Isoform 1 at 409.800kDa and Isoform 2 at 217.794kDa Multiple other isoforms in ref: Human Molecular Genetics, 2005, Vol. 14, No. 15 2155–2165.

Forme physique

Affinity purified
Purified rabbit serum in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Human ductal carcinoma tissue

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Arran K Turnbull et al.
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