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  • Computational Design and Synthesis of Novel Fluoro-Analogs of Combretastatins A-4 and A-1.

Computational Design and Synthesis of Novel Fluoro-Analogs of Combretastatins A-4 and A-1.

Journal of fluorine chemistry (2018-01-10)
Yao Zong, Christie Shea, Katherine Maffucci, Iwao Ojima
PMID29311752
ABSTRACT

Combretastatin A-1 (CA-1) and combretastatin A-4 (CA-4) isolated from the African bush willow

MATERIALS
Product Number
Brand
Product Description
529214
Sigma-Aldrich
2-Fluoro-4-(trifluoromethyl)benzaldehyde, 98%
470112
Sigma-Aldrich
4-(Difluoromethoxy)benzaldehyde, 95%