- Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release.
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release.
Pain-producing animal venoms contain evolutionarily honed toxins that can be exploited to study and manipulate somatosensory and nociceptive signaling pathways. From a functional screen, we have identified a secreted phospholipase A2 (sPLA2)-like protein, BomoTx, from the Brazilian lancehead pit viper (