- Dialkylformamidines: depurination resistant N6-protecting group for deoxyadenosine.
Dialkylformamidines: depurination resistant N6-protecting group for deoxyadenosine.
Nucleic acids research (1983-11-25)
B C Froehler, M D Matteucci
PMID6606157
ABSTRACT
Sterically hindered N6-dialkylformamidine protected deoxyadenosine is more stable to acidic depurination than N6-benzoyldeoxyadenosine and is potentially a valuable protecting group in the synthesis of deoxyoligonucleotides.
MATERIALS