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  • Focal parietal necrosis of the sigmoid due to atypical neuroleptics: a case report.

Focal parietal necrosis of the sigmoid due to atypical neuroleptics: a case report.

Acta gastro-enterologica Belgica (2012-08-09)
Arnaud Devresse, Philippe Maldague, Bruno Coulier, Frédéric Pierard, Isabelle Gielen
ABSTRACT

We present the case of a 26-year-old man with schizoid personality disorder who suffered from a very focal and transparietal necrosis of the sigmoid after an overdose of atypical neuroleptics. This is a singular, rather unknown and potentially lethal side effect of these drugs. The physiopathology of this complication is multifactorial.

MATERIALS
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Sigma-Aldrich
Trazodone hydrochloride, ≥99% (HPLC), powder