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PLA0195

Sigma-Aldrich

Rabbit anti-MOV10 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

MGC2948, Moloney leukemia virus 10, Mov10, Mov10 (Moloney leukemia virus 10, fSAP113, functional spliceosome-associated protein 113, gb110, homolog, homolog (mouse), moloney leukemia virus 10 protein, mouse) homolog

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human, mouse

technique(s)

immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_066014.1

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... MOV10(4343)

Immunogen

The epitope recognized by PLA0195 maps to a region between residue 953 and 1003 of human Moloney leukemia virus 10, homolog using the numbering given in entry NP_066014.1 (GeneID 4343).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

Moloney leukemia virus 10 protein (MOV10) is putative RNA helicase that has been identified as a factor associated with argonaute (Ago) containing complexes. Ago complexes play a central in micro RNA (miRNA) and short-interference RNA (siRNA) silencing.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Julia Kornienko et al.
Nature communications, 14(1), 4312-4312 (2023-07-19)
Severe forms of dilated cardiomyopathy (DCM) are associated with point mutations in the alternative splicing regulator RBM20 that are frequently located in the arginine/serine-rich domain (RS-domain). Such mutations can cause defective splicing and cytoplasmic mislocalization, which leads to the formation
Alessandra Zappulo et al.
Nature communications, 8(1), 583-583 (2017-09-21)
Protein subcellular localization is fundamental to the establishment of the body axis, cell migration, synaptic plasticity, and a vast range of other biological processes. Protein localization occurs through three mechanisms: protein transport, mRNA localization, and local translation. However, the relative

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