M5890

Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucuronate

≥98% (GC)

• Empirical Formula (Hill Notation): C₁₅H₂₀O₁₁
• CAS Number: 7355-18-2
• Molecular Weight: 376.31
• EC Number: 230-880-3
• MDL number: MFCD00069834
• UNSPSC Code: 12352201
• PubChem Substance ID: 24897053
• NACRES: NA.25

Properties

• biological source: synthetic (organic)
• Assay: ≥98% (GC)
• form: powder
• optical activity: [α]20/D 8.1 to 9.5 °, c = 1% (w/v) in chloroform
• technique(s): gas chromatography (GC): suitable
• storage temp.: 2-8°C
• SMILES string: COC(=O)C1OC(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
• InChI: 1S/C15H20O11/c1-6(16)22-10-11(23-7(2)17)13(24-8(3)18)15(25-9(4)19)26-12(10)14(20)21-5/h10-13,15H,1-5H3
• InChI key: DPOQCELSZBSZGX-UHFFFAOYSA-N

Description

Application

Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucuronate has been used in a study to assess design and synthesis of a water-soluble glucuronide derivatives of camptothecin for cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy. It has also been used in a study to investigate the synthesis and role of glycosylthio heterocycles in carbohydrate chemistry.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves