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EMU158101

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Abcb5

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TTTGCCAACAGGGATAAGCAGGCGCTCAAGCGTGCTGGAAAGATAGCAACAGAAGCTGTGGAGAACATACGTACGGTAGTGTCATTAACAAGAGAGAGAGCCTTTGAGCAAATGTATGAGGAGACACTTCAGACTCAACACAGGCCAGCACATCCTAACTTCTCATGTGACTTCACCAAGAGAAAATCAAGTGCTAACACAACCAAAAAGTATAGGTTCCCACGCAATCATCTGATCCTCAGTGAGGGCACAGAATCAACTTATTTCTGAAAGAAAGTTGAATGGAAGAGAGAAAATAGGATGGCTCACTCTTTTATGTTAGATCTCTAAGAGAGCTTAAATGTAAAGCAAATGTGTACTCTGCGCTTATTTAATGGCCCTTATCACCCTGCCTCTGTCTTTGTATTTATCAGAAAGATAGTTTTGTTCTCATTTCCACTGACGTCTGTAGTCTGCACCACCCACAGATTGCCACTACATATTCTATGAGTGTTAGGTCATGATGGAAAT

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Ge Yang et al.
Molecular medicine reports, 12(3), 3930-3936 (2015-06-06)
MicroRNAs (miRNAs) are small non-coding RNAs, which are important in the development of multidrug resistance in cancer by regulating gene expression at the post‑transcriptional level. The present study investigated the functional effects of miR‑522 in chemoresistant colon cancer cells. The
Naruji Kugimiya et al.
Journal of cellular and molecular medicine, 19(7), 1569-1581 (2015-02-18)
c-MYC overexpression is frequently observed in various cancers including colon cancer and regulates many biological activities such as aberrant cell proliferation, apoptosis, genomic instability, immortalization and drug resistance. However, the mechanism by which c-MYC confers drug resistance remains to be

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